| 1. Round | 16/07/2021 | Newell's Old Boys II | - | Talleres de Córdoba II | 2:1 | ||||
| 2. Round | 23/07/2021 | Talleres de Córdoba II | - | Arsenal de Sarandí II | 1:1 | ||||
| 3. Round | 27/07/2021 | Central Córdoba SdE II | - | Talleres de Córdoba II | 1:2 |  |
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| 4. Round | 02/08/2021 | Talleres de Córdoba II | - | Boca Juniors II | 1:1 | ||||
| 5. Round | 06/08/2021 | Banfield II | - | Talleres de Córdoba II | 3:0 | ||||
| 6. Round | 13/08/2021 | Talleres de Córdoba II | - | San Lorenzo II | 1:0 | |
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| 7. Round | 20/08/2021 | Unión de Santa Fe II | - | Talleres de Córdoba II | 2:2 | |
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| 8. Round | 26/08/2021 | Argentinos Juniors II | - | Talleres de Córdoba II | 0:1 | |
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| 9. Round | 30/08/2021 | Talleres de Córdoba II | - | Estudiantes II | 1:2 | ||||
| 10. Round | 03/09/2021 | Patronato de Paraná II | - | Talleres de Córdoba II | 0:2 | |
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| 11. Round | 10/09/2021 | Talleres de Córdoba II | - | Platense II | 0:0 | ||||
| 12. Round | 20/09/2021 | Racing Club II | - | Talleres de Córdoba II | 2:0 | ||||
| 13. Round | 24/09/2021 | Talleres de Córdoba II | - | Rosario Central II | 3:1 | ||||
| 14. Round | 01/10/2021 | Defensa y Justicia II | - | Talleres de Córdoba II | 2:2 |
Argentina