| 1. Round | 16/07/2021 | Lanús II | - | Atlético Tucumán II | 0:0 | ||||
| 2. Round | 23/07/2021 | Colón de Santa Fe II | - | Lanús II | 0:1 | ||||
| 3. Round | 27/07/2021 | Lanús II | - | River Plate II | 0:1 | ||||
| 4. Round | 30/07/2021 | Lanús II | - | Unión de Santa Fe II | 2:1 | ||||
| 5. Round | 06/08/2021 | Huracán II | - | Lanús II | 0:2 | ||||
| 6. Round | 13/08/2021 | Lanús II | - | Godoy Cruz II | 5:1 | ||||
| 14. Round | 30/09/2021 | Lanús II | - | Central Córdoba SdE II | 4:0 |
Argentina