| 1. Round | 25/07/2020 | Club Necaxa | - | UANL Tigres | 0:3 | ||||
| 2. Round | 01/08/2020 | FC Juárez | - | Club Necaxa | 1:0 | ||||
| 3. Round | 08/08/2020 | Club Necaxa | - | CF América | 1:1 | ||||
| 4. Round | 11/08/2020 | Club Necaxa | - | Mazatlán FC | 1:0 | ||||
| 5. Round | 16/08/2020 | CF Monterrey | - | Club Necaxa | 1:1 | ||||
| 6. Round | 22/08/2020 | Club Necaxa | - | Santos Laguna | 2:1 | ||||
| 7. Round | 30/08/2020 | Cruz Azul | - | Club Necaxa | 3:0 | ||||
| 8. Round | 05/09/2020 | Club Necaxa | - | Club León | 0:2 | ||||
| 9. Round | 08/09/2020 | Atlético San Luis | - | Club Necaxa | 2:1 | ||||
| 10. Round | 12/09/2020 | Club Necaxa | - | Deportivo Guadalajara | 1:2 | ||||
| 11. Round | 19/09/2020 | Club Necaxa | - | Puebla FC | 0:1 | ||||
| 13. Round | 03/10/2020 | Atlas Guadalajara | - | Club Necaxa | 0:1 | ||||
| 14. Round | 17/10/2020 | Club Necaxa | - | Club Tijuana | 2:0 |  |
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| 16. Round | 31/10/2020 | Club Necaxa | - | Deportivo Toluca | 3:2 | ||||
| 17. Round | 07/11/2020 | CF Pachuca | - | Club Necaxa | 0:1 |
Argentina