1. Round | 16/07/2021 | Arsenal de Sarandí II | - | San Lorenzo II | 0:1 | ||||
2. Round | 23/07/2021 | San Lorenzo II | - | Central Córdoba SdE II | 1:0 | ||||
4. Round | 30/07/2021 | San Lorenzo II | - | Banfield II | 2:3 | ||||
6. Round | 13/08/2021 | Talleres de Córdoba II | - | San Lorenzo II | 1:0 | ||||
19. Round | 31/10/2021 | San Lorenzo II | - | Godoy Cruz II | 0:1 |