| 1. Round | 08/08/2022 | West Bromwich Albion U21 | - | Newcastle United U21 | 2:1 |  |
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| 2. Round | 15/08/2022 | Newcastle United U21 | - | Stoke City U21 | 0:1 |  |
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| 4. Round | 26/08/2022 | Newcastle United U21 | - | Derby County U21 | 4:0 | ||||
| 7. Round | 30/09/2022 | Middlesbrough FC U21 | - | Newcastle United U21 | 1:1 | ||||
| 5. Round | 14/10/2022 | Aston Villa U21 | - | Newcastle United U21 | 1:2 | ||||
| 10. Round | 31/10/2022 | Newcastle United U21 | - | Sunderland AFC U21 | 1:1 | ||||
| 13. Round | 13/01/2023 | Southampton FC U21 | - | Newcastle United U21 | 4:1 | |
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| 14. Round | 30/01/2023 | Sunderland AFC U21 | - | Newcastle United U21 | 2:1 | ||||
| 15. Round | 13/02/2023 | Newcastle United U21 | - | Leeds United U21 | 2:2 | ||||
| 17. Round | 24/02/2023 | Stoke City U21 | - | Newcastle United U21 | 2:2 | ||||
| 18. Round | 06/03/2023 | Newcastle United U21 | - | West Bromwich Albion U21 | 2:5 | ||||
| 19. Round | 18/03/2023 | Nottingham Forest U21 | - | Newcastle United U21 | 3:1 | ||||
| 20. Round | 03/04/2023 | Newcastle United U21 | - | Middlesbrough FC U21 | 0:0 | ||||
| 21. Round | 17/04/2023 | Newcastle United U21 | - | Norwich City U21 | 4:3 | ||||
| 22. Round | 24/04/2023 | Derby County U21 | - | Newcastle United U21 | 1:4 | |
England