| 1. Round | 02/03/2021 | Talleres de Córdoba | - | Atlético Rafaela | 6:5 pso |  |
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| Round of 32 | 07/04/2021 | Talleres de Córdoba | - | Vélez Sarsfield | 3:1 pso |  |
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| Round of 16 | 12/08/2021 | Estudiantes de Río Cuarto | - | Talleres de Córdoba | 5:6 pso | |
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| Quarter-finals | 30/09/2021 | Temperley | - | Talleres de Córdoba | 1:2 | |
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| Semi-finals | 02/12/2021 | Talleres de Córdoba | - | Godoy Cruz | 1:0 | ||||
| Final | 09/12/2021 | Talleres de Córdoba | - | Boca Juniors | 4:5 pso |
Uruguay