| 1. Round | 13/09/2020 | Adanaspor | - | İstanbulspor AŞ | 1:0 | ||||
| 2. Round | 20/09/2020 | İstanbulspor AŞ | - | Altay Izmir | 2:1 |  |
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| 4. Round | 02/10/2020 | İstanbulspor AŞ | - | Bandırmaspor | 2:1 | ||||
| 7. Round | 25/10/2020 | İstanbulspor AŞ | - | Eskişehirspor | 3:0 | ||||
| 12. Round | 04/12/2020 | Tuzlaspor | - | İstanbulspor AŞ | 2:0 | ||||
| 14. Round | 14/12/2020 | Menemen Belediyespor | - | İstanbulspor AŞ | 1:2 | ||||
| 16. Round | 26/12/2020 | Boluspor | - | İstanbulspor AŞ | 0:2 | ||||
| 9. Round | 30/12/2020 | İstanbulspor AŞ | - | Adana Demirspor | 3:1 | ||||
| 17. Round | 03/01/2021 | İstanbulspor AŞ | - | Ankaraspor | 5:3 |
Turkey