| 1. Round | 11/02/2012 | Lanús | - | San Lorenzo | 4:1 |  |
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| 7. Round | 24/03/2012 | Atlético Rafaela | - | San Lorenzo | 2:1 | ||||
| 9. Round | 09/04/2012 | Racing Club | - | San Lorenzo | 1:1 | ||||
| 10. Round | 14/04/2012 | San Lorenzo | - | Godoy Cruz | 3:0 | ||||
| 11. Round | 22/04/2012 | Banfield | - | San Lorenzo | 1:1 |  |
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| 13. Round | 06/05/2012 | All Boys | - | San Lorenzo | 0:0 | ||||
| 14. Round | 13/05/2012 | San Lorenzo | - | Olimpo de Bahía Blanca | 1:1 | |
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| 15. Round | 20/05/2012 | Unión de Santa Fe | - | San Lorenzo | 1:0 | ||||
| 16. Round | 27/05/2012 | San Lorenzo | - | Newell's Old Boys | 3:2 | ||||
| 17. Round | 10/06/2012 | Tigre | - | San Lorenzo | 3:1 | ||||
| 18. Round | 17/06/2012 | Independiente | - | San Lorenzo | 0:0 | ||||
| 19. Round | 24/06/2012 | San Lorenzo | - | San Martín de San Juan | 3:1 |
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