| 13. Round | 27/09/2021 | Argentinos Juniors II | - | Racing Club II | 2:1 | ||||
| 18. Round | 24/10/2021 | Rosario Central II | - | Racing Club II | 1:2 | ||||
| 20. Round | 05/11/2021 | Atlético Tucumán II | - | Racing Club II | 2:1 | ||||
| 21. Round | 17/11/2021 | Racing Club II | - | Colón de Santa Fe II | 1:1 | ||||
| 22. Round | 23/11/2021 | River Plate II | - | Racing Club II | 1:2 | ||||
| 23. Round | 27/11/2021 | Racing Club II | - | Lanús II | 1:1 | ||||
| 24. Round | 02/12/2021 | Huracán II | - | Racing Club II | 0:3 |  |
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| 25. Round | 11/12/2021 | Racing Club II | - | Godoy Cruz II | 2:1 |
Argentina
Paraguay