| 1. Round | 13/08/2022 | Manisa FK | - | Boluspor | 0:1 | ||||
| 3. Round | 27/08/2022 | Manisa FK | - | Denizlispor | 3:2 | ||||
| 4. Round | 05/09/2022 | Samsunspor | - | Manisa FK | 0:1 | ||||
| 5. Round | 11/09/2022 | Manisa FK | - | Yeni Malatyaspor | 2:2 | ||||
| 6. Round | 18/09/2022 | Bodrum FK | - | Manisa FK | 1:1 | ||||
| 7. Round | 02/10/2022 | Manisa FK | - | Adanaspor | 3:2 | ||||
| 8. Round | 08/10/2022 | Eyüpspor | - | Manisa FK | 4:0 | ||||
| 9. Round | 15/10/2022 | Manisa FK | - | Altay Izmir | 1:1 | ||||
| 10. Round | 22/10/2022 | Manisa FK | - | Çaykur Rizespor | 2:2 |  |
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| 11. Round | 31/10/2022 | Gençlerbirliği | - | Manisa FK | 1:3 |  |
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| 12. Round | 05/11/2022 | Manisa FK | - | Sakaryaspor | 2:1 | ||||
| 13. Round | 13/11/2022 | Bandırmaspor | - | Manisa FK | 2:1 | ||||
| 14. Round | 19/11/2022 | Manisa FK | - | BB Erzurumspor | 0:0 | ||||
| 15. Round | 28/11/2022 | Altınordu FK | - | Manisa FK | 1:3 |
Germany