| 1. Round | 05/08/2022 | İstanbulspor AŞ | - | Trabzonspor | 0:2 | ||||
| 2. Round | 13/08/2022 | Kayserispor | - | İstanbulspor AŞ | 1:0 | ||||
| 3. Round | 22/08/2022 | İstanbulspor AŞ | - | Konyaspor | 0:4 | ||||
| 4. Round | 27/08/2022 | Alanyaspor | - | İstanbulspor AŞ | 0:1 | ||||
| 6. Round | 11/09/2022 | Sivasspor | - | İstanbulspor AŞ | 1:1 | ||||
| 7. Round | 17/09/2022 | İstanbulspor AŞ | - | Beşiktaş | 2:2 | ||||
| 8. Round | 03/10/2022 | Fatih Karagümrük | - | İstanbulspor AŞ | 1:2 | ||||
| 9. Round | 08/10/2022 | İstanbulspor AŞ | - | MKE Ankaragücü | 1:2 | ||||
| 10. Round | 16/10/2022 | İstanbul Başakşehir | - | İstanbulspor AŞ | 2:0 | ||||
| 11. Round | 21/10/2022 | Antalyaspor | - | İstanbulspor AŞ | 2:1 | ||||
| 12. Round | 30/10/2022 | İstanbulspor AŞ | - | Fenerbahçe | 2:5 | ||||
| 13. Round | 05/11/2022 | Giresunspor | - | İstanbulspor AŞ | 3:2 |  |
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| 14. Round | 13/11/2022 | İstanbulspor AŞ | - | Hatayspor | 0:1 | ||||
| 15. Round | 25/12/2022 | Galatasaray | - | İstanbulspor AŞ | 2:1 | ||||
| 16. Round | 28/12/2022 | İstanbulspor AŞ | - | Kasımpaşa SK | 2:1 | ||||
| 17. Round | 05/01/2023 | Adana Demirspor | - | İstanbulspor AŞ | 6:0 | ||||
| 19. Round | 15/01/2023 | Ümraniyespor | - | İstanbulspor AŞ | 0:2 | ||||
| 20. Round | 22/01/2023 | Trabzonspor | - | İstanbulspor AŞ | 4:0 |
Turkey