| 3. Round | 06/09/2009 | Giresunspor | - | Karşıyaka SK | 0:1 |  |
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| 7. Round | 05/10/2009 | Dardanelspor | - | Karşıyaka SK | 1:5 | |
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| 8. Round | 10/10/2009 | Karşıyaka SK | - | Konyaspor | 2:2 | |
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| 13. Round | 22/11/2009 | Karşıyaka SK | - | Mersin Idmanyurdu | 3:0 | |
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| 14. Round | 29/11/2009 | Çaykur Rizespor | - | Karşıyaka SK | 0:2 | |
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| 15. Round | 06/12/2009 | Karşıyaka SK | - | Kocaelispor | 2:0 | |
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| 21. Round | 08/02/2010 | Altay Izmir | - | Karşıyaka SK | 0:2 | |
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| 22. Round | 14/02/2010 | Karşıyaka SK | - | Gaziantep Bld.Spor | 1:2 | |
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| 24. Round | 28/02/2010 | Karşıyaka SK | - | Dardanelspor | 2:1 | |
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| 29. Round | 04/04/2010 | Bucaspor | - | Karşıyaka SK | 3:2 | |
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| 32. Round | 25/04/2010 | Kocaelispor | - | Karşıyaka SK | 1:2 | |
Turkey