| 2. Round | 28/08/2022 | Shakhtar Donetsk | - | Kryvbas Kryvyi Rih | 1:0 | ||||
| 3. Round | 02/09/2022 | Rukh Lviv | - | Shakhtar Donetsk | 0:1 | ||||
| 4. Round | 10/09/2022 | Shakhtar Donetsk | - | Chernomorets Odessa | 2:1 | ||||
| 5. Round | 01/10/2022 | Metalist Kharkiv | - | Shakhtar Donetsk | 1:6 |  |
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| 7. Round | 16/10/2022 | Shakhtar Donetsk | - | Dinamo Kiev | 3:1 | |
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| 8. Round | 19/10/2022 | Shakhtar Donetsk | - | Kolos Kovalivka | 3:0 | ||||
| 10. Round | 29/10/2022 | Shakhtar Donetsk | - | FK Oleksandriya | 2:2 | ||||
| 9. Round | 28/02/2023 | FC Mynai | - | Shakhtar Donetsk | 1:4 | ||||
| 16. Round | 05/03/2023 | Metalist 1925 Kharkiv | - | Shakhtar Donetsk | 0:7 | |
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| 17. Round | 12/03/2023 | Kryvbas Kryvyi Rih | - | Shakhtar Donetsk | 0:3 | ||||
| 23. Round | 28/04/2023 | Kolos Kovalivka | - | Shakhtar Donetsk | 1:3 | ||||
| 24. Round | 03/05/2023 | Shakhtar Donetsk | - | FC Mynai | 1:0 | ||||
| 25. Round | 07/05/2023 | FK Oleksandriya | - | Shakhtar Donetsk | 1:1 | ||||
| 26. Round | 13/05/2023 | Inhulets Petrove | - | Shakhtar Donetsk | 0:2 | ||||
| 27. Round | 19/05/2023 | Shakhtar Donetsk | - | NK Veres | 2:1 | |
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| 28. Round | 24/05/2023 | Zorya Lugansk | - | Shakhtar Donetsk | 0:3 | ||||
| 29. Round | 28/05/2023 | Shakhtar Donetsk | - | SK Dnipro-1 | 3:0 |
Ukraine