| 1. Round | 14/09/2020 | Norwich City U23 | - | Reading FC U23 | 3:0 |  |
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| 2. Round | 18/09/2020 | Reading FC U23 | - | Fulham FC U23 | 0:4 | |
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| 3. Round | 25/09/2020 | Aston Villa U23 | - | Reading FC U23 | 1:2 |  |
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| 4. Round | 02/10/2020 | West Bromwich Albion U23 | - | Reading FC U23 | 1:1 | ||||
| 5. Round | 16/10/2020 | Reading FC U23 | - | Leeds United U23 | 3:2 | ||||
| 6. Round | 26/10/2020 | Stoke City U23 | - | Reading FC U23 | 4:1 | |
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| 7. Round | 30/10/2020 | Reading FC U23 | - | Newcastle United U23 | 3:2 | ||||
| 8. Round | 09/11/2020 | Crystal Palace U23 | - | Reading FC U23 | 6:0 | |
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| 10. Round | 27/11/2020 | Middlesbrough FC U23 | - | Reading FC U23 | 2:3 | |
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| 15. Round | 22/01/2021 | Fulham FC U23 | - | Reading FC U23 | 0:3 | ||||
| 16. Round | 29/01/2021 | Reading FC U23 | - | Aston Villa U23 | 3:1 |
England