| 1. Round | 05/06/2022 | Independiente II | - | San Lorenzo II | 0:1 | ||||
| 2. Round | 09/06/2022 | Talleres de Córdoba II | - | Independiente II | 0:4 | ||||
| 3. Round | 15/06/2022 | Independiente II | - | Argentinos Juniors II | 0:3 | ||||
| 4. Round | 19/06/2022 | Estudiantes II | - | Independiente II | 1:1 | ||||
| 5. Round | 26/06/2022 | Independiente II | - | Patronato de Paraná II | 7:1 | ||||
| 9. Round | 19/07/2022 | Independiente II | - | Defensa y Justicia II | 0:0 | ||||
| 10. Round | 23/07/2022 | Atlético Tucumán II | - | Independiente II | 1:2 |
Argentina