| 1. Round | 27/07/2000 | San Lorenzo | - | Gimnasia de La Plata | 3:0 | ||||
| 2. Round | 05/08/2000 | Newell's Old Boys | - | San Lorenzo | 1:0 |  |
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| 8. Round | 23/09/2000 | River Plate | - | San Lorenzo | 2:2 | ||||
| 13. Round | 02/11/2000 | San Lorenzo | - | Talleres de Córdoba | 1:1 | |
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| 14. Round | 09/11/2000 | CA Los Andes | - | San Lorenzo | 0:1 | ||||
| 15. Round | 18/11/2000 | San Lorenzo | - | Estudiantes | 1:1 | ||||
| 16. Round | 25/11/2000 | San Lorenzo | - | Chacarita Juniors | 4:0 | ||||
| 17. Round | 02/12/2000 | Boca Juniors | - | San Lorenzo | 1:0 | |
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| 18. Round | 09/12/2000 | San Lorenzo | - | Argentinos Juniors | 2:1 | |
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| 19. Round | 14/12/2000 | Unión de Santa Fe | - | San Lorenzo | 0:0 | |
Argentina