1. Round | 12/02/2021 | Independiente II | - | Lanús II | 4:1 | ||||
2. Round | 19/02/2021 | Patronato de Paraná II | - | Independiente II | 1:3 | ||||
3. Round | 26/02/2021 | Independiente II | - | Gimnasia de La Plata II | 1:1 | ||||
4. Round | 05/03/2021 | Newell's Old Boys II | - | Independiente II | 1:2 | ||||
5. Round | 12/03/2021 | Independiente II | - | Sarmiento de Junín II | 4:2 | ||||
6. Round | 19/03/2021 | Vélez Sarsfield II | - | Independiente II | 2:0 | ||||
7. Round | 29/03/2021 | Independiente II | - | Boca Juniors II | 1:1 | ||||
8. Round | 02/04/2021 | Talleres de Córdoba II | - | Independiente II | 1:3 | ||||
9. Round | 09/04/2021 | Racing Club II | - | Independiente II | 3:1 | ||||
10. Round | 16/04/2021 | Independiente II | - | Defensa y Justicia II | 2:3 | ||||
11. Round | 23/04/2021 | Unión de Santa Fe II | - | Independiente II | 1:1 | ||||
12. Round | 30/04/2021 | Independiente II | - | Atlético Tucumán II | 1:0 | ||||
13. Round | 07/05/2021 | Huracán II | - | Independiente II | 0:0 |