| 1. Round | 16/01/2016 | Huachipato | - | Universidad de Concepción | 3:0 |  |
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| 2. Round | 23/01/2016 | Deportes Iquique | - | Huachipato | 1:1 |  |
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| 3. Round | 30/01/2016 | Huachipato | - | Unión Española | 3:3 | |
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| 4. Round | 08/02/2016 | Unión La Calera | - | Huachipato | 1:2 | |
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| 5. Round | 14/02/2016 | Huachipato | - | Santiago Wanderers | 3:2 | |
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| 6. Round | 21/02/2016 | Antofagasta | - | Huachipato | 3:0 | ||||
| 7. Round | 28/02/2016 | Universidad Católica | - | Huachipato | 2:2 | ||||
| 8. Round | 05/03/2016 | Huachipato | - | San Marcos | 1:1 |  |
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| 10. Round | 02/04/2016 | Colo-Colo | - | Huachipato | 1:1 | ||||
| 11. Round | 05/04/2016 | Huachipato | - | San Luis | 3:3 | |
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| 12. Round | 09/04/2016 | Cobresal | - | Huachipato | 3:2 | |
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| 14. Round | 23/04/2016 | Palestino | - | Huachipato | 1:1 | |
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| 15. Round | 29/04/2016 | Huachipato | - | Universidad de Chile | 4:2 | |
Venezuela