| 1. Round | 15/08/2021 | Bursaspor | - | Adanaspor | 1:1 | ||||
| 2. Round | 21/08/2021 | Adanaspor | - | Gençlerbirliği | 0:0 | ||||
| 3. Round | 28/08/2021 | Keçiörengücü | - | Adanaspor | 2:0 | ||||
| 5. Round | 15/09/2021 | Denizlispor | - | Adanaspor | 2:0 | ||||
| 6. Round | 19/09/2021 | Adanaspor | - | Ümraniyespor | 0:0 | ||||
| 7. Round | 25/09/2021 | BB Erzurumspor | - | Adanaspor | 3:1 | ||||
| 8. Round | 02/10/2021 | Adanaspor | - | Bandırmaspor | 1:5 | ||||
| 12. Round | 07/11/2021 | Balıkesirspor | - | Adanaspor | 1:2 | ||||
| 16. Round | 11/12/2021 | Boluspor | - | Adanaspor | 0:0 |  |
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| 19. Round | 24/12/2021 | Adanaspor | - | Kocaelispor | 2:0 | ||||
| 20. Round | 08/01/2022 | Adanaspor | - | Bursaspor | 3:1 | ||||
| 21. Round | 17/01/2022 | Gençlerbirliği | - | Adanaspor | 0:3 |
Turkey