| 1. Round | 13/09/2020 | Liverpool FC U23 | - | Everton FC U23 | 1:0 | ||||
| 2. Round | 21/09/2020 | Everton FC U23 | - | Leicester City U23 | 3:0 |  |
|||
| 3. Round | 28/09/2020 | Everton FC U23 | - | Derby County U23 | 4:1 | |
|||
| 4. Round | 04/10/2020 | Everton FC U23 | - | Manchester City U23 | 1:2 | ||||
| 5. Round | 19/10/2020 | Everton FC U23 | - | Tottenham Hotspur U23 | 0:0 | ||||
| 6. Round | 23/10/2020 | Manchester United U23 | - | Everton FC U23 | 2:1 | ||||
| 8. Round | 08/11/2020 | Everton FC U23 | - | Chelsea FC U23 | 2:0 | ||||
| 9. Round | 20/11/2020 | Arsenal FC U23 | - | Everton FC U23 | 1:0 | ||||
| 10. Round | 27/11/2020 | Blackburn Rovers U23 | - | Everton FC U23 | 1:1 | ||||
| 11. Round | 14/12/2020 | Everton FC U23 | - | West Ham United U23 | 2:1 | ||||
| 12. Round | 18/12/2020 | Brighton & Hove Albion U23 | - | Everton FC U23 | 2:2 | ||||
| 14. Round | 18/01/2021 | Everton FC U23 | - | Liverpool FC U23 | 1:1 | ||||
| 17. Round | 05/02/2021 | Manchester City U23 | - | Everton FC U23 | 3:1 | ||||
| 19. Round | 22/02/2021 | Everton FC U23 | - | Manchester United U23 | 3:1 | ||||
| 21. Round | 12/03/2021 | Chelsea FC U23 | - | Everton FC U23 | 2:1 | |
|||
| 22. Round | 21/03/2021 | Everton FC U23 | - | Arsenal FC U23 | 1:1 |
Wales