| 2. Round | 26/02/2025 | River Plate II | - | Instituto de Córdoba II | 2:2 |  |
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| 3. Round | 06/03/2025 | San Lorenzo II | - | River Plate II | 2:0 | ||||
| 4. Round | 13/03/2025 | River Plate II | - | Independiente II | 2:1 | |
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| 6. Round | 27/03/2025 | River Plate II | - | Lanús II | 3:1 | ||||
| 7. Round | 03/04/2025 | San Martín de San Juan II | - | River Plate II | 1:3 | ||||
| 8. Round | 09/04/2025 | River Plate II | - | Atlético Tucumán II | 3:0 | |
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| 9. Round | 15/04/2025 | Deportivo Riestra II | - | River Plate II | 1:1 | ||||
| 10. Round | 22/04/2025 | River Plate II | - | Rosario Central II | 1:4 | ||||
| 11. Round | 30/04/2025 | Sarmiento de Junín II | - | River Plate II | 2:2 | |
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| 12. Round | 06/05/2025 | River Plate II | - | Talleres de Córdoba II | 3:2 | ||||
| 13. Round | 14/05/2025 | Gimnasia de La Plata II | - | River Plate II | 0:1 | ||||
| 14. Round | 21/05/2025 | River Plate II | - | Boca Juniors II | 2:1 | ||||
| 15. Round | 28/05/2025 | River Plate II | - | Vélez Sarsfield II | 1:0 |
Argentina