| 1. Round | 18/10/2020 | Guaireña FC | - | Libertad | 0:3 |  |
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| 2. Round | 25/10/2020 | Libertad | - | Sol de América | 0:2 | ||||
| 3. Round | 31/10/2020 | Cerro Porteño | - | Libertad | 1:0 |  |
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| 4. Round | 07/11/2020 | Libertad | - | River Plate | 3:1 | |
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| 7. Round | 20/11/2020 | San Lorenzo | - | Libertad | 2:2 | |
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| 8. Round | 29/11/2020 | Libertad | - | 12 de Octubre de Itauguá | 3:0 | ||||
| 10. Round | 11/12/2020 | Libertad | - | Guaraní | 1:1 | ||||
| 11. Round | 19/12/2020 | Libertad | - | Club Olimpia | 2:1 | |
Paraguay