| 2. Round | 16/02/2022 | Gimnasia de La Plata II | - | San Lorenzo II | 2:1 | ||||
| 3. Round | 21/02/2022 | San Lorenzo II | - | Defensa y Justicia II | 0:4 | ||||
| 4. Round | 26/02/2022 | Argentinos Juniors II | - | San Lorenzo II | 2:0 | ||||
| 5. Round | 04/03/2022 | San Lorenzo II | - | River Plate II | 0:4 | ||||
| 6. Round | 12/03/2022 | Talleres de Córdoba II | - | San Lorenzo II | 2:3 |
Argentina