| 7. Round | 03/09/2022 | Leyton Orient | - | Tranmere Rovers | 2:0 | ||||
| 15. Round | 15/10/2022 | Leyton Orient | - | Northampton Town | 0:0 | ||||
| 13. Round | 25/10/2022 | Leyton Orient | - | Gillingham FC | 2:0 | ||||
| 17. Round | 29/10/2022 | Leyton Orient | - | Salford City | 1:0 | ||||
| 18. Round | 12/11/2022 | Harrogate Town | - | Leyton Orient | 0:2 | ||||
| 25. Round | 02/01/2023 | Northampton Town | - | Leyton Orient | 1:0 | ||||
| 26. Round | 07/01/2023 | Leyton Orient | - | Doncaster Rovers | 1:0 | ||||
| 27. Round | 14/01/2023 | Leyton Orient | - | Barrow AFC | 0:0 | ||||
| 40. Round | 07/04/2023 | Salford City | - | Leyton Orient | 0:2 | ||||
| 36. Round | 25/04/2023 | Mansfield Town | - | Leyton Orient | 1:2 |
England
Guyana