| 1. Round | 31/07/2021 | East Fife FC | - | Queen's Park FC | 1:1 | ||||
| 2. Round | 07/08/2021 | Queen's Park FC | - | Cove Rangers | 2:0 | ||||
| 3. Round | 14/08/2021 | Queen's Park FC | - | Dumbarton FC | 3:0 | ||||
| 4. Round | 21/08/2021 | Alloa Athletic | - | Queen's Park FC | 1:1 |  |
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| 5. Round | 28/08/2021 | Falkirk FC | - | Queen's Park FC | 0:1 | ||||
| 12. Round | 30/10/2021 | Cove Rangers | - | Queen's Park FC | 3:3 | ||||
| 13. Round | 06/11/2021 | Queen's Park FC | - | East Fife FC | 1:1 | ||||
| 14. Round | 13/11/2021 | Queen's Park FC | - | Clyde FC | 0:0 | |
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| 15. Round | 20/11/2021 | Peterhead FC | - | Queen's Park FC | 2:1 | ||||
| 16. Round | 04/12/2021 | Queen's Park FC | - | Falkirk FC | 6:0 | ||||
| 17. Round | 29/12/2021 | Airdrieonians FC | - | Queen's Park FC | 1:0 | ||||
| 36. Round | 30/04/2022 | Queen's Park FC | - | Falkirk FC | 1:1 |
Scotland