| 7. Round | 20/08/2021 | Arsenal de Sarandí II | - | Racing Club II | 3:1 |  |
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| 8. Round | 24/08/2021 | Racing Club II | - | Central Córdoba SdE II | 3:0 | ||||
| 9. Round | 27/08/2021 | Boca Juniors II | - | Racing Club II | 4:0 | ||||
| 10. Round | 06/09/2021 | Racing Club II | - | Banfield II | 1:2 | ||||
| 11. Round | 10/09/2021 | San Lorenzo II | - | Racing Club II | 0:0 | ||||
| 13. Round | 27/09/2021 | Argentinos Juniors II | - | Racing Club II | 2:1 | ||||
| 15. Round | 09/10/2021 | Patronato de Paraná II | - | Racing Club II | 2:1 | ||||
| 16. Round | 14/10/2021 | Racing Club II | - | Platense II | 1:3 | |
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| 18. Round | 24/10/2021 | Rosario Central II | - | Racing Club II | 1:2 | ||||
| 21. Round | 17/11/2021 | Racing Club II | - | Colón de Santa Fe II | 1:1 | ||||
| 22. Round | 23/11/2021 | River Plate II | - | Racing Club II | 1:2 | ||||
| 23. Round | 27/11/2021 | Racing Club II | - | Lanús II | 1:1 |
Argentina