| 3. Round | 26/07/2021 | Vélez Sarsfield II | - | Defensa y Justicia II | 0:0 | ||||
| 4. Round | 02/08/2021 | Atlético Tucumán II | - | Vélez Sarsfield II | 3:0 | ||||
| 6. Round | 13/08/2021 | River Plate II | - | Vélez Sarsfield II | 1:2 | ||||
| 13. Round | 24/09/2021 | Sarmiento de Junín II | - | Vélez Sarsfield II | 0:4 | ||||
| 20. Round | 05/11/2021 | Vélez Sarsfield II | - | San Lorenzo II | 2:0 | ||||
| 22. Round | 25/11/2021 | Vélez Sarsfield II | - | Argentinos Juniors II | 1:1 | ||||
| 23. Round | 29/11/2021 | Estudiantes II | - | Vélez Sarsfield II | 2:3 | ||||
| 24. Round | 06/12/2021 | Vélez Sarsfield II | - | Patronato de Paraná II | 1:0 |
Argentina