6. Round | 13/08/2021 | Rosario Central II | - | Independiente II | 3:1 | ||||
7. Round | 20/08/2021 | Independiente II | - | Defensa y Justicia II | 1:1 | ||||
8. Round | 24/08/2021 | Atlético Tucumán II | - | Independiente II | 0:0 | ||||
9. Round | 27/08/2021 | Independiente II | - | Colón de Santa Fe II | 0:0 | ||||
10. Round | 06/09/2021 | River Plate II | - | Independiente II | 4:0 | ||||
11. Round | 13/09/2021 | Independiente II | - | Lanús II | 1:0 | ||||
12. Round | 17/09/2021 | Huracán II | - | Independiente II | 2:0 | ||||
19. Round | 29/10/2021 | Newell's Old Boys II | - | Independiente II | 1:0 | ||||
20. Round | 08/11/2021 | Independiente II | - | Arsenal de Sarandí II | 1:1 | ||||
21. Round | 19/11/2021 | Central Córdoba SdE II | - | Independiente II | 2:3 | ||||
22. Round | 24/11/2021 | Independiente II | - | Boca Juniors II | 0:0 | ||||
23. Round | 01/12/2021 | Banfield II | - | Independiente II | 1:1 | ||||
24. Round | 06/12/2021 | Independiente II | - | San Lorenzo II | 1:0 | ||||
25. Round | 10/12/2021 | Talleres de Córdoba II | - | Independiente II | 3:3 |