| 2. Round | 15/02/2022 | Defensa y Justicia II | - | Racing Club II | 1:0 | ||||
| 3. Round | 21/02/2022 | San Lorenzo II | - | Defensa y Justicia II | 0:4 | ||||
| 5. Round | 04/03/2022 | Banfield II | - | Defensa y Justicia II | 2:0 | ||||
| 8. Round | 01/04/2022 | Defensa y Justicia II | - | River Plate II | 2:0 | ||||
| 9. Round | 08/04/2022 | Talleres de Córdoba II | - | Defensa y Justicia II | 1:2 | ||||
| 12. Round | 25/04/2022 | Defensa y Justicia II | - | Platense II | 1:1 |
Argentina