| 8. Round | 24/08/2021 | Defensa y Justicia II | - | Newell's Old Boys II | 1:1 | ||||
| 11. Round | 09/09/2021 | Boca Juniors II | - | Defensa y Justicia II | 3:2 | ||||
| 13. Round | 24/09/2021 | San Lorenzo II | - | Defensa y Justicia II | 0:2 | ||||
| 17. Round | 18/10/2021 | Patronato de Paraná II | - | Defensa y Justicia II | 2:2 | ||||
| 22. Round | 24/11/2021 | Atlético Tucumán II | - | Defensa y Justicia II | 4:1 |
Argentina