| 2. Round | 21/08/2021 | Athletic Club | - | FC Barcelona | 1:1 | ||||
| 5. Round | 20/09/2021 | FC Barcelona | - | Granada CF | 1:1 | ||||
| 6. Round | 23/09/2021 | Cádiz CF | - | FC Barcelona | 0:0 | ||||
| 7. Round | 26/09/2021 | FC Barcelona | - | Levante UD | 3:0 | ||||
| 11. Round | 27/10/2021 | Rayo Vallecano | - | FC Barcelona | 1:0 | ||||
| 14. Round | 20/11/2021 | FC Barcelona | - | Espanyol Barcelona | 1:0 |
Austria