| 25. Round | 29/12/2021 | Oxford United | - | AFC Wimbledon | 3:0 | ||||
| 38. Round | 12/03/2022 | AFC Wimbledon | - | Lincoln City | 0:2 |  |
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| 39. Round | 19/03/2022 | Cheltenham Town | - | AFC Wimbledon | 3:1 | ||||
| 41. Round | 02/04/2022 | Sheffield Wednesday | - | AFC Wimbledon | 2:1 | ||||
| 24. Round | 05/04/2022 | AFC Wimbledon | - | Charlton Athletic | 1:1 |  |
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| 42. Round | 09/04/2022 | AFC Wimbledon | - | Milton Keynes Dons | 1:1 |
England