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| 1st(1st leg) | Morocco | - | Liberia | 3:1 | ||
| 2nd (2nd leg) | Liberia | - | Morocco | 0:5 | ||
| 1st(1st leg): 22/03/1981 | 2nd (2nd leg): 04/04/1981 | Winner: Morocco | ||||
| 1st(1st leg) | Cameroon | - | Togo | 4:0 | ||
| 2nd (2nd leg) | Togo | - | Cameroon | 2:2 | ||
| 1st(1st leg): 05/04/1981 | 2nd (2nd leg): 19/04/1981 | Winner: Cameroon | ||||
| 1st(1st leg) | Kenya | - | Egypt | 3:5 | ||
| 2nd (2nd leg) | Egypt | - | Kenya | 2:0 | ||
| 1st(1st leg): 05/04/1981 | 2nd (2nd leg): 18/04/1981 | Winner: Egypt | ||||
| 1st(1st leg) | Congo DR | - | Mozambique | 2:1 | ||
| 2nd (2nd leg) | Mozambique | - | Congo DR | 3:3 | ||
| 1st(1st leg): 05/04/1981 | 2nd (2nd leg): 19/04/1981 | Winner: Congo DR | ||||
| 1st(1st leg) | Guinea | - | Equatorial Guinea | dnp | ||
| 2nd (2nd leg) | Equatorial Guinea | - | Guinea | dnp | ||
| 1st(1st leg): 05/04/1981 | 2nd (2nd leg): 19/04/1981 | Winner: Guinea | ||||
| 1st(1st leg) | Madagascar | - | Tanzania | dnp | ||
| 2nd (2nd leg) | Tanzania | - | Madagascar | dnp | ||
| 1st(1st leg): 05/04/1981 | 2nd (2nd leg): 19/04/1981 | Winner: Madagascar | ||||
| 1st(1st leg) | Algeria | - | Mali | 5:1 | ||
| 2nd (2nd leg) | Mali | - | Algeria | 3:0 | ||
| 1st(1st leg): 10/04/1981 | 2nd (2nd leg): 19/04/1981 | Winner: Algeria | ||||
| 1st(1st leg) | Ghana | - | Congo | 1:1 | ||
| 2nd (2nd leg) | Congo | - | Ghana | 0:1 | ||
| 1st(1st leg): 11/04/1981 | 2nd (2nd leg): 26/04/1981 | Winner: Ghana | ||||
| 1st(1st leg) | Zimbabwe | - | Zambia | 0:1 | ||
| 2nd (2nd leg) | Zambia | - | Zimbabwe | 2:0 | ||
| 1st(1st leg): 11/04/1981 | 2nd (2nd leg): 25/04/1981 | Winner: Zambia | ||||
| 1st(1st leg) | Tunisia | - | Senegal | 1:0 | ||
| 2nd (2nd leg) | Senegal | - | Tunisia | 0:0 | ||
| 1st(1st leg): 12/04/1981 | 2nd (2nd leg): 26/04/1981 | Winner: Tunisia | ||||
| 1st(1st leg) | Ethiopia | - | Rwanda | 1:0 | ||
| 2nd (2nd leg) | Rwanda | - | Ethiopia | 4:3 pso | ||
| 1st(1st leg): 26/04/1981 | 2nd (2nd leg): 10/05/1981 | Winner: Rwanda | ||||
