1st(1st leg) Goiás - Coritiba FC 1:0 (0:0)
2nd (2nd leg) Coritiba FC - Goiás 1:1 (0:1)
1st(1st leg): 28/02/2018 22:30 2nd (2nd leg): 14/03/2018 22:30 Winner: Goiás
1st(1st leg) São Paulo FC - CR Brasil - AL 2:0 (2:0)
2nd (2nd leg) CR Brasil - AL - São Paulo FC 0:3 (0:1)
1st(1st leg): 28/02/2018 22:30 2nd (2nd leg): 14/03/2018 22:30 Winner: São Paulo FC
1st(1st leg) Náutico - PE - Cuiabá - MT 2:1 (0:0)
2nd (2nd leg) Cuiabá - MT - Náutico - PE 0:1 (0:0)
1st(1st leg): 28/02/2018 22:30 2nd (2nd leg): 15/03/2018 00:45 Winner: Náutico - PE
1st(1st leg) Ponte Preta - Sampaio Corrêa - MA 0:0 (0:0)
2nd (2nd leg) Sampaio Corrêa - MA - Ponte Preta 3:5 (0:0, 0:0) pso
1st(1st leg): 28/02/2018 22:30 2nd (2nd leg): 15/03/2018 22:15 Winner: Ponte Preta
1st(1st leg) Bragantino - SP - Vitória - BA 1:0 (1:0)
2nd (2nd leg) Vitória - BA - Bragantino - SP 3:0 (1:0)
1st(1st leg): 28/02/2018 22:30 2nd (2nd leg): 15/03/2018 22:15 Winner: Vitória - BA
1st(1st leg) Ferroviário - CE - Vila Nova - GO 1:1 (1:0)
2nd (2nd leg) Vila Nova - GO - Ferroviário - CE 0:1 (0:1)
1st(1st leg): 28/02/2018 23:30 2nd (2nd leg): 15/03/2018 23:30 Winner: Ferroviário - CE
1st(1st leg) Athletico Paranaense - Ceará SC 0:0 (0:0)
2nd (2nd leg) Ceará SC - Athletico Paranaense 5:6 (1:1, 1:1) pso
1st(1st leg): 01/03/2018 00:30 2nd (2nd leg): 16/03/2018 00:30 Winner: Athletico Paranaense
1st(1st leg) Figueirense - Atlético Mineiro 0:1 (0:1)
2nd (2nd leg) Atlético Mineiro - Figueirense 4:2 (1:1, 1:2) pso
1st(1st leg): 01/03/2018 00:45 2nd (2nd leg): 15/03/2018 00:45 Winner: Atlético Mineiro
1st(1st leg) Internacional - Cianorte - PR 2:0 (0:0)
2nd (2nd leg) Cianorte - PR - Internacional 0:2 (0:1)
1st(1st leg): 01/03/2018 22:15 2nd (2nd leg): 14/03/2018 22:30 Winner: Internacional
1st(1st leg) Fluminense RJ - Avaí FC 1:2 (1:1)
2nd (2nd leg) Avaí FC - Fluminense RJ 1:0 (0:0)
1st(1st leg): 01/03/2018 22:15 2nd (2nd leg): 16/03/2018 00:30 Winner: Avaí FC