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| 1st(1st leg) | Sunshine Stars | - | Al Ahly SC | 3:3 (1:2) | ||
| 2nd (2nd leg) | Al Ahly SC | - | Sunshine Stars | 1:0 (1:0) | ||
| 1st(1st leg): 06/10/2012 15:00 | 2nd (2nd leg): 21/10/2012 19:00 | Winner: Al Ahly SC | ||||
| 1st(1st leg) | TP Mazembe | - | Espérance de Tunis | 0:0 (0:0) | ||
| 2nd (2nd leg) | Espérance de Tunis | - | TP Mazembe | 1:0 (0:0) | ||
| 1st(1st leg): 07/10/2012 15:30 | 2nd (2nd leg): 20/10/2012 20:30 | Winner: Espérance de Tunis | ||||
