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| 31/10/2018 | 14:30 | MFK Karviná | - | FK Jablonec | 1:0 (0:0) | |
| 16:30 | Viktoria Plzeň | - | Baník Ostrava | 2:3 (1:0, 2:2) aet | ||
| 07/11/2018 | 15:00 | 1. FK Příbram | - | Bohemians Praha 1905 | 1:2 (0:1) | |
| 15/11/2018 | 16:00 | Sigma Olomouc | - | FC Fastav Zlín | 2:1 (0:0) | |
| 16:30 | Slovan Liberec | - | 1. FC Slovácko | 1:0 (1:0) | ||
| 16/11/2018 | 16:00 | FK Dukla Praha | - | FK Teplice | 1:3 (0:2) | |
| 17:30 | Slavia Praha | - | MFK Chrudim | 3:1 (2:0) | ||
| 28/11/2018 | 14:45 | SFC Opava | - | AC Sparta Praha | 3:4 (0:0, 0:0, 0:0) pso |
