 |
 |
|
|
| 05/02/2022 | 12:45 | Olympiakos Volou | - | Olympiakos Piraeus II | 2:3 (1:2) | |
| 12:45 | PAOK Saloniki II | - | Apollon Lárissa | 3:0 (1:0) | ||
| 15:00 | Niki Volou FC | - | Panserraikos | 1:0 (1:0) | ||
| 06/02/2022 | 12:45 | Thesprotos | - | Apollon Pontou | 1:2 (1:0) | |
| 12:45 | Almopos Arideas | - | AEP Iraklis FC | 0:2 (0:0) | ||
| 12:45 | AO Trikala | - | AE Lárissa | 0:1 (0:0) | ||
| 15:00 | AO Kavala | - | Veria FC | 0:2 (0:2) | ||
| 18:00 | Xanthi FC | - | Anagennisi Karditsa | 5:2 (4:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Veria FC | 16 | 11 | 3 | 2 | 37:14 | 23 | 36 |
| 2 |
|
AE Lárissa | 16 | 9 | 6 | 1 | 21:5 | 16 | 33 |
| 3 |
|
Anagennisi Karditsa | 16 | 9 | 3 | 4 | 29:17 | 12 | 30 |
| 4 |
|
Xanthi FC | 16 | 8 | 5 | 3 | 25:12 | 13 | 29 |
| 5 |
|
Olympiakos Piraeus II | 16 | 6 | 7 | 3 | 20:17 | 3 | 25 |
| 6 |
|
AEP Iraklis FC | 16 | 5 | 9 | 2 | 17:11 | 6 | 24 |
| 7 |
|
Niki Volou FC | 16 | 6 | 5 | 5 | 20:12 | 8 | 23 |
| 8 |
|
PAOK Saloniki II | 16 | 5 | 7 | 4 | 21:16 | 5 | 22 |
| 9 |
|
Almopos Arideas | 16 | 6 | 3 | 7 | 21:17 | 4 | 21 |
| 10 |
|
Thesprotos | 16 | 5 | 3 | 8 | 21:20 | 1 | 18 |
| 11 |
|
Apollon Pontou | 16 | 4 | 5 | 7 | 20:24 | -4 | 17 |
| 12 |
|
Olympiakos Volou | 16 | 4 | 4 | 8 | 21:26 | -5 | 16 |
| 13 |
|
AO Trikala | 16 | 4 | 4 | 8 | 13:25 | -12 | 16 |
| 14 |
|
Pierikos Katerini | 16 | 3 | 6 | 7 | 16:20 | -4 | 15 |
| 15 |
|
Panserraikos | 16 | 2 | 7 | 7 | 16:25 | -9 | 13 |
| 16 |
|
Apollon Lárissa | 16 | 2 | 7 | 7 | 12:23 | -11 | 13 |
| 17 |
|
AO Kavala | 16 | 3 | 4 | 9 | 11:57 | -46 | 13 |
| Playoffs | |
| Relegation |
