 |
 |
|
|
| 04/03/2021 | 23:00 | Gallos Blancos | - | CF Pachuca | 0:3 (0:2) | |
| 05/03/2021 | 22:00 | Club Necaxa | - | Puebla FC | 3:2 (2:1) | |
| 06/03/2021 | 16:00 | Atlas Guadalajara | - | Cruz Azul | 0:1 (0:1) | |
| 18:00 | Pumas UNAM | - | UANL Tigres | 0:4 (0:3) | ||
| 07/03/2021 | 23:00 | Atlético San Luis | - | CF América | 1:0 (1:0) | |
| 08/03/2021 | 21:45 | Deportivo Toluca | - | FC Juárez | 0:0 (0:0) | |
| 23:00 | CF Monterrey | - | Santos Laguna | 2:2 (2:0) | ||
| 09/03/2021 | 01:00 | Club Tijuana | - | Deportivo Guadalajara | 2:1 (1:0) | |
| 01:00 | Club León | - | Mazatlán FC | 1:2 (0:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UANL Tigres | 9 | 7 | 1 | 1 | 21:3 | 18 | 22 |
| 2 |
|
Atlas Guadalajara | 9 | 6 | 2 | 1 | 16:11 | 5 | 20 |
| 3 |
|
Deportivo Guadalajara | 9 | 6 | 1 | 2 | 20:8 | 12 | 19 |
| 4 |
|
Pumas UNAM | 9 | 6 | 1 | 2 | 14:8 | 6 | 19 |
| 5 |
|
CF Monterrey | 9 | 5 | 1 | 3 | 25:11 | 14 | 16 |
| 6 |
|
CF América | 9 | 4 | 3 | 2 | 13:10 | 3 | 15 |
| 7 |
|
Deportivo Toluca | 9 | 4 | 3 | 2 | 9:8 | 1 | 15 |
| 8 |
|
CF Pachuca | 9 | 4 | 2 | 3 | 12:10 | 2 | 14 |
| 9 |
|
Cruz Azul | 9 | 3 | 4 | 2 | 10:11 | -1 | 13 |
| 10 |
|
Club Tijuana | 9 | 3 | 3 | 3 | 9:9 | 0 | 12 |
| 11 |
|
Mazatlán FC | 9 | 3 | 3 | 3 | 9:13 | -4 | 12 |
| 12 |
|
Gallos Blancos | 9 | 3 | 1 | 5 | 11:16 | -5 | 10 |
| 13 |
|
Atlético San Luis | 9 | 2 | 2 | 5 | 11:20 | -9 | 8 |
| 14 |
|
Club León | 9 | 2 | 2 | 5 | 9:19 | -10 | 8 |
| 15 |
|
FC Juárez | 9 | 1 | 3 | 5 | 8:13 | -5 | 6 |
| 16 |
|
Santos Laguna | 9 | 1 | 3 | 5 | 10:17 | -7 | 6 |
| 17 |
|
Club Necaxa | 9 | 1 | 2 | 6 | 7:19 | -12 | 5 |
| 18 |
|
Puebla FC | 9 | 0 | 3 | 6 | 5:13 | -8 | 3 |
| Playoffs |
