 |
 |
|
|
| 21/10/2022 | 21:00 | Guaireña FC | - | Sol de América | 0:0 (0:0) | |
| 23:30 | Tacuary | - | 12 de Octubre de Itauguá | 5:1 (1:0) | ||
| 22/10/2022 | 21:00 | Sportivo Ameliano | - | Resistencia SC | 3:2 (0:1) | |
| 23:30 | Club Olimpia | - | General Caballero DJLM | 2:1 (0:1) | ||
| 23/10/2022 | 21:00 | Guaraní | - | Cerro Porteño | 1:2 (1:1) | |
| 23:30 | Libertad | - | Club Nacional | 0:1 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Nacional | 18 | 12 | 5 | 1 | 25:11 | 14 | 41 |
| 2 |
|
Club Olimpia | 18 | 12 | 3 | 3 | 30:16 | 14 | 39 |
| 3 |
|
Cerro Porteño | 18 | 11 | 5 | 2 | 26:11 | 15 | 38 |
| 4 |
|
Libertad | 18 | 8 | 3 | 7 | 29:23 | 6 | 27 |
| 5 |
|
Guaireña FC | 18 | 6 | 6 | 6 | 22:21 | 1 | 24 |
| 6 |
|
Tacuary | 18 | 7 | 3 | 8 | 21:20 | 1 | 24 |
| 7 |
|
General Caballero DJLM | 18 | 6 | 3 | 9 | 21:24 | -3 | 21 |
| 8 |
|
Sportivo Ameliano | 18 | 6 | 2 | 10 | 21:25 | -4 | 20 |
| 9 |
|
Guaraní | 18 | 5 | 5 | 8 | 18:24 | -6 | 20 |
| 10 |
|
Resistencia SC | 18 | 5 | 5 | 8 | 15:24 | -9 | 20 |
| 11 |
|
Sol de América | 18 | 5 | 4 | 9 | 18:27 | -9 | 19 |
| 12 |
|
12 de Octubre de Itauguá | 18 | 2 | 2 | 14 | 11:31 | -20 | 8 |
| Copa Libertadores |
