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| 10/02/2021 | FC Solothurn | - | SC Kriens | 0:3 dec. | ||
| 16:30 | FC Aarau | - | FC Sion | 4:2 (1:0, 2:2) aet | ||
| 17/02/2021 | 16:30 | FC Winterthur | - | FC Basel 1893 | 6:2 (2:0) | |
| 24/02/2021 | 16:30 | Grasshopper Club Zürich | - | FC Lausanne-Sport | 2:0 (0:0) | |
| 10/03/2021 | 16:30 | FC Chiasso | - | FC Luzern | 1:2 (0:0) | |
| 07/04/2021 | 17:00 | Vevey United | - | Servette FC | 2:4 (1:0) | |
| 17:00 | FC Monthey | - | FC Lugano | 0:3 (0:2) | ||
| 08/04/2021 | 17:00 | FC St. Gallen | - | BSC Young Boys | 4:1 (1:0) |
