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| 1st(1st leg) | Team Aargau | - | BSC Young Boys | 1:2 (0:2) | ||
| 2nd (2nd leg) | BSC Young Boys | - | Team Aargau | 2:1 (2:0) | ||
| 1st(1st leg): 28/05/2022 12:30 | 2nd (2nd leg): 04/06/2022 12:30 | Winner: BSC Young Boys | ||||
| 1st(1st leg) | FCO St. Gallen/Wil | - | Servette FC | 3:0 (2:0) | ||
| 2nd (2nd leg) | Servette FC | - | FCO St. Gallen/Wil | 1:0 (0:0) | ||
| 1st(1st leg): 28/05/2022 13:00 | 2nd (2nd leg): 04/06/2022 13:00 | Winner: FCO St. Gallen/Wil | ||||
| 1st(1st leg) | Team FC Luzern/SC Kriens | - | FC Basel | 1:6 (1:3) | ||
| 2nd (2nd leg) | FC Basel | - | Team FC Luzern/SC Kriens | 2:3 (1:2) | ||
| 1st(1st leg): 28/05/2022 13:00 | 2nd (2nd leg): 04/06/2022 13:00 | Winner: FC Basel | ||||
| 1st(1st leg) | Grasshopper Club Zürich | - | FC Zürich | 0:4 (0:2) | ||
| 2nd (2nd leg) | FC Zürich | - | Grasshopper Club Zürich | 1:4 (1:1) | ||
| 1st(1st leg): 29/05/2022 13:00 | 2nd (2nd leg): 04/06/2022 18:00 | Winner: FC Zürich | ||||
