15/03/2022 15:00 Slovan Bratislava - Zlaté Moravce 2:0 (0:0)
18:00 FK AS Trenčín - MFK Skalica 2:0 (0:0)
16/03/2022 13:00 MŠK Žilina - Spartak Trnava 1:4 (0:0, 0:0) pso
15:00 FK Senica - FK Pohronie 3:2 (1:2)