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| 19/02/2021 | 16:00 | İstanbul Başakşehir | - | Trabzonspor | 0:1 (0:0) | |
| 20/02/2021 | 10:30 | Kasımpaşa SK | - | Fatih Karagümrük | 3:2 (1:1) | |
| 13:00 | Denizlispor | - | Gençlerbirliği | 1:0 (1:0) | ||
| 13:00 | Yeni Malatyaspor | - | Konyaspor | 2:3 (2:0) | ||
| 16:00 | Alanyaspor | - | Galatasaray | 0:1 (0:1) | ||
| 21/02/2021 | 10:30 | BB Erzurumspor | - | Hatayspor | 1:3 (0:2) | |
| 13:00 | Gaziantep FK | - | Antalyaspor | 0:0 (0:0) | ||
| 13:00 | Sivasspor | - | Kayserispor | 2:0 (1:0) | ||
| 16:00 | Fenerbahçe | - | Göztepe | 0:1 (0:1) | ||
| 22/02/2021 | 16:00 | MKE Ankaragücü | - | Çaykur Rizespor | 1:1 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Galatasaray | 25 | 17 | 3 | 5 | 50:19 | 31 | 54 |
| 2 |
|
Beşiktaş | 24 | 16 | 3 | 5 | 53:26 | 27 | 51 |
| 3 |
|
Fenerbahçe | 25 | 16 | 3 | 6 | 47:27 | 20 | 51 |
| 4 |
|
Trabzonspor | 25 | 14 | 6 | 5 | 32:24 | 8 | 48 |
| 5 |
|
Alanyaspor | 25 | 12 | 6 | 7 | 40:24 | 16 | 42 |
| 6 |
|
Hatayspor | 25 | 12 | 6 | 7 | 42:30 | 12 | 42 |
| 7 |
|
Gaziantep FK | 25 | 10 | 9 | 6 | 37:29 | 8 | 39 |
| 8 |
|
Fatih Karagümrük | 25 | 10 | 7 | 8 | 39:34 | 5 | 37 |
| 9 |
|
Antalyaspor | 25 | 7 | 12 | 6 | 24:29 | -5 | 33 |
| 10 |
|
Göztepe | 25 | 8 | 8 | 9 | 35:31 | 4 | 32 |
| 11 |
|
Sivasspor | 24 | 7 | 10 | 7 | 28:29 | -1 | 31 |
| 12 |
|
Konyaspor | 24 | 8 | 6 | 10 | 32:30 | 2 | 30 |
| 13 |
|
Yeni Malatyaspor | 25 | 7 | 9 | 9 | 32:34 | -2 | 30 |
| 14 |
|
Kasımpaşa SK | 25 | 8 | 5 | 12 | 29:40 | -11 | 29 |
| 15 |
|
Çaykur Rizespor | 25 | 6 | 9 | 10 | 30:42 | -12 | 27 |
| 16 |
|
Kayserispor | 25 | 6 | 7 | 12 | 17:30 | -13 | 25 |
| 17 |
|
BB Erzurumspor | 25 | 6 | 7 | 12 | 24:39 | -15 | 25 |
| 18 |
|
İstanbul Başakşehir | 25 | 6 | 6 | 13 | 28:44 | -16 | 24 |
| 19 |
|
Denizlispor | 25 | 5 | 6 | 14 | 23:43 | -20 | 21 |
| 20 |
|
MKE Ankaragücü | 24 | 5 | 5 | 14 | 27:40 | -13 | 20 |
| 21 |
|
Gençlerbirliği | 24 | 5 | 5 | 14 | 20:45 | -25 | 20 |
| Champions League Quali. | |
| Relegation |
