 |
 |
| Quarter-finals | ||||||
|---|---|---|---|---|---|---|
| 05/10/2022 | 15:00 | Santos Laguna | - | Atlas Guadalajara | 1:2 (1:1) | |
| 17:00 | CF América | - | Deportivo Guadalajara | 2:1 (2:0) | ||
| 06/10/2022 | 16:00 | Pumas UNAM | - | Deportivo Toluca | 0:1 (0:0) | |
| 07/10/2022 | 05:00 | Club Tijuana | - | CF Pachuca | 2:1 (2:1) | |
| 08/10/2022 | 16:00 | Deportivo Guadalajara | - | CF América | 1:2 (1:1) | |
| 17:30 | Atlas Guadalajara | - | Santos Laguna | 3:3 (2:0) | ||
| 09/10/2022 | 15:00 | CF Pachuca | - | Club Tijuana | 2:1 (1:0) | |
| 17:30 | Deportivo Toluca | - | Pumas UNAM | 2:0 (0:0) | ||
| Semi-finals | ||||||
| 13/10/2022 | 15:00 | CF América | - | Deportivo Toluca | 1:1 (0:0) | |
| 15:00 | Atlas Guadalajara | - | CF Pachuca | 1:0 (0:0) | ||
| 16/10/2022 | 15:00 | CF Pachuca | - | Atlas Guadalajara | 2:0 (1:0) | |
| 17:30 | Deportivo Toluca | - | CF América | 0:1 (0:1) | ||
| Final | ||||||
| 19/10/2022 | 16:00 | CF América | - | CF Pachuca | 5:2 (0:2) | |
| 22/10/2022 | 16:00 | CF Pachuca | - | CF América | 2:0 (0:0) | |
