 |
 |
| Quarter-finals | ||||||
|---|---|---|---|---|---|---|
| 05/05/2021 | 15:00 | Atlas Guadalajara | - | CF América | 3:1 (2:0) | |
| 16:00 | Club León | - | CF Monterrey | 0:1 (0:1) | ||
| 06/05/2021 | 15:00 | Deportivo Toluca | - | Club Tijuana | 1:0 (1:0) | |
| 17:00 | FC Juárez | - | CF Pachuca | 1:1 (1:0) | ||
| 08/05/2021 | 15:00 | CF Monterrey | - | Club León | 3:2 (3:1) | |
| 17:00 | CF América | - | Atlas Guadalajara | 0:2 (0:0) | ||
| 09/05/2021 | 18:00 | CF Pachuca | - | FC Juárez | 0:0 (0:0) | |
| 10/05/2021 | 05:00 | Club Tijuana | - | Deportivo Toluca | 2:2 (1:0) | |
| Semi-finals | ||||||
| 12/05/2021 | 15:00 | Deportivo Toluca | - | CF Pachuca | 0:2 (0:1) | |
| 13/05/2021 | 15:00 | Atlas Guadalajara | - | CF Monterrey | 1:2 (1:0) | |
| 15/05/2021 | 16:00 | CF Pachuca | - | Deportivo Toluca | 0:2 (0:0) | |
| 16/05/2021 | 15:00 | CF Monterrey | - | Atlas Guadalajara | 1:0 (0:0) | |
| Final | ||||||
| 20/05/2021 | 17:00 | CF Pachuca | - | CF Monterrey | 0:0 (0:0) | |
| 23/05/2021 | 23:30 | CF Monterrey | - | CF Pachuca | 2:1 (0:1, 1:1) aet | |
