1. Round
05/01/2022 15:00 Belenenses SAD - SC Farense 3:3 (2:1)
26/01/2022 11:00 FC Famalicão - Vitória Guimarães 2:3 (1:2)
27/01/2022 17:00 Sporting CP - FC Vizela 1:1 (1:1)
29/01/2022 15:00 CS Marítimo - Académica de Coimbra 1:0 (0:0)
2. Round
09/01/2022 11:00 FC Vizela - Belenenses SAD 0:1 (0:1)
15:00 Académica de Coimbra - FC Famalicão 3:0 (1:0)
11/01/2022 11:00 Vitória Guimarães - Sporting CP 5:1 (1:0)
26/03/2022 11:00 SC Farense - CS Marítimo 0:0 (0:0)
3. Round
15/01/2022 11:00 Belenenses SAD - CS Marítimo 1:1 (0:1)
11:00 FC Famalicão - SC Farense 0:0 (0:0)
15:00 Sporting CP - Académica de Coimbra 4:3 (2:0)
15/02/2022 11:00 FC Vizela - Vitória Guimarães 1:1 (0:0)
4. Round
18/01/2022 11:00 CS Marítimo - FC Famalicão 1:3 (0:2)
14:00 Vitória Guimarães - Belenenses SAD 3:0 (1:0)
15:00 Académica de Coimbra - FC Vizela 0:1 (0:0)
05/03/2022 15:00 SC Farense - Sporting CP 0:1 (0:1)
5. Round
22/01/2022 11:00 FC Vizela - SC Farense 3:1 (2:0)
15:00 Belenenses SAD - FC Famalicão 1:3 (1:2)
15:00 Vitória Guimarães - Académica de Coimbra 1:2 (0:2)
23/01/2022 11:00 Sporting CP - CS Marítimo 0:0 (0:0)
6. Round
01/02/2022 11:00 CS Marítimo - FC Vizela 0:3 (0:1)
11:00 FC Famalicão - Sporting CP 2:0 (2:0)
11:00 SC Farense - Vitória Guimarães 2:0 (1:0)
17:00 Belenenses SAD - Académica de Coimbra 5:2 (4:0)
7. Round
05/02/2022 11:00 Académica de Coimbra - SC Farense 1:3 (0:2)
11:00 FC Vizela - FC Famalicão 2:1 (0:1)
11:00 Vitória Guimarães - CS Marítimo 1:5 (0:2)
07/02/2022 11:00 Sporting CP - Belenenses SAD 0:2 (0:0)
8. Round
10/02/2022 14:00 Vitória Guimarães - FC Famalicão 1:2 (0:2)
11/02/2022 11:00 FC Vizela - Sporting CP 3:0 (3:0)
12/02/2022 11:00 Académica de Coimbra - CS Marítimo 0:3 (0:1)
15:00 SC Farense - Belenenses SAD 1:3 (0:2)
9. Round
18/02/2022 11:00 CS Marítimo - SC Farense 1:0 (0:0)
19/02/2022 11:00 Belenenses SAD - FC Vizela 2:1 (1:0)
11:00 Sporting CP - Vitória Guimarães 0:0 (0:0)
15:00 FC Famalicão - Académica de Coimbra 0:3 (0:2)
10. Round
26/02/2022 11:00 CS Marítimo - Belenenses SAD 3:1 (2:1)
15:00 Académica de Coimbra - Sporting CP 2:1 (2:0)
15:00 Vitória Guimarães - FC Vizela 3:1 (2:0)
28/02/2022 11:00 SC Farense - FC Famalicão 0:5 (0:2)
11. Round
23/02/2022 11:00 Sporting CP - SC Farense 2:1 (1:1)
04/03/2022 15:00 FC Vizela - Académica de Coimbra 5:0 (3:0)
05/03/2022 11:00 FC Famalicão - CS Marítimo 1:1 (0:1)
25/03/2022 11:00 Belenenses SAD - Vitória Guimarães 5:1 (3:0)
12. Round
11/03/2022 15:00 FC Famalicão - Belenenses SAD 1:1 (0:1)
12/03/2022 11:00 CS Marítimo - Sporting CP 1:1 (1:1)
11:00 SC Farense - FC Vizela 2:1 (1:0)
15:00 Académica de Coimbra - Vitória Guimarães 4:1 (1:1)
13. Round
18/03/2022 11:00 Vitória Guimarães - SC Farense 1:1 (0:1)
19/03/2022 11:00 FC Vizela - CS Marítimo 0:1 (0:0)
15:00 Académica de Coimbra - Belenenses SAD 0:3 (0:2)
21/03/2022 16:00 Sporting CP - FC Famalicão 2:5 (0:0)
14. Round
02/04/2022 11:00 SC Farense - Académica de Coimbra 3:0 (1:0)
04/04/2022 16:00 Belenenses SAD - Sporting CP 3:0 (1:0)
16:00 CS Marítimo - Vitória Guimarães 3:1 (2:0)
16:00 FC Famalicão - FC Vizela 3:2 (1:2)
U23 Liga Revelação
U23 Liga Revelação