20. Round | 26/01/2022 | San Fernando CD | - | Real Betis B | 1:0 | ![]() |
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16. Round | 02/02/2022 | CE Sabadell | - | Real Betis B | 0:0 | ||||
22. Round | 05/02/2022 | UE Cornellà | - | Real Betis B | 2:0 | ||||
23. Round | 13/02/2022 | Real Betis B | - | Atlético Baleares | 0:2 | ![]() |
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19. Round | 16/02/2022 | Real Betis B | - | Sevilla Atlético | 0:1 | ||||
24. Round | 19/02/2022 | Villarreal CF B | - | Real Betis B | 3:0 | ![]() |
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26. Round | 05/03/2022 | UE Costa Brava | - | Real Betis B | 1:2 | ![]() |
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27. Round | 13/03/2022 | Real Betis B | - | Algeciras CF | 2:3 | ||||
29. Round | 27/03/2022 | Real Betis B | - | FC Barcelona B | 1:2 | ![]() |
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30. Round | 03/04/2022 | UCAM Murcia CF | - | Real Betis B | 1:0 | ![]() |
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31. Round | 09/04/2022 | Real Betis B | - | CE Sabadell | 0:4 | ||||
32. Round | 17/04/2022 | RB Linense | - | Real Betis B | 1:0 | ![]() |
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33. Round | 24/04/2022 | Sevilla Atlético | - | Real Betis B | 1:0 | ![]() |
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35. Round | 06/05/2022 | Real Betis B | - | CD Alcoyano | 3:2 |