| 1. Round | 29/08/2021 | Toulouse FC [Youth B] | - | Nîmes Olympique [Youth B] | 3:0 | ||||
| 2. Round | 05/09/2021 | Nîmes Olympique [Youth B] | - | Pau FC [Youth B] | 2:2 |  |
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| 3. Round | 11/09/2021 | FC Istres [Youth B] | - | Nîmes Olympique [Youth B] | 3:3 | |
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| 4. Round | 18/09/2021 | Nîmes Olympique [Youth B] | - | Marignane Gignac [Youth B] | 3:4 |  |
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| 5. Round | 26/09/2021 | SA Mérignac [Youth B] | - | Nîmes Olympique [Youth B] | 2:2 | ||||
| 6. Round | 03/10/2021 | Nîmes Olympique [Youth B] | - | AS Muret [Youth B] | 2:1 |
France