| 3. Round | 18/09/2022 | FC Cartagena B | - | Cádiz CF B | 1:1 | ||||
| 6. Round | 09/10/2022 | Recreativo Granada | - | FC Cartagena B | 1:2 |  |
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| 8. Round | 23/10/2022 | FC Cartagena B | - | Mar Menor CF | 1:1 | ||||
| 11. Round | 20/11/2022 | Xerez DFC | - | FC Cartagena B | 0:2 | |
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| 14. Round | 11/12/2022 | FC Cartagena B | - | Atlético Mancha Real | 3:0 |  |
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| 19. Round | 29/01/2023 | FC Cartagena B | - | Atlético Sanluqueño CF | 2:1 | ||||
| 25. Round | 12/03/2023 | Mar Menor CF | - | FC Cartagena B | 1:2 | ||||
| 30. Round | 16/04/2023 | FC Cartagena B | - | Juventud Torremolinos | 2:3 | |
Spain