| 11. Round | 28/11/2020 | SD Huesca | - | Sevilla FC | 0:1 | ||||
| 12. Round | 05/12/2020 | Sevilla FC | - | Real Madrid | 0:1 | ||||
| 13. Round | 12/12/2020 | Getafe CF | - | Sevilla FC | 0:1 |  |
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| 15. Round | 22/12/2020 | Valencia CF | - | Sevilla FC | 0:1 | ||||
| 17. Round | 02/01/2021 | Real Betis | - | Sevilla FC | 1:1 | ||||
| 18. Round | 09/01/2021 | Sevilla FC | - | Real Sociedad | 3:2 | ||||
| 20. Round | 23/01/2021 | Sevilla FC | - | Cádiz CF | 3:0 | ||||
| 21. Round | 30/01/2021 | SD Eibar | - | Sevilla FC | 0:2 | ||||
| 22. Round | 06/02/2021 | Sevilla FC | - | Getafe CF | 3:0 | ||||
| 23. Round | 13/02/2021 | Sevilla FC | - | SD Huesca | 1:0 | ||||
| 24. Round | 22/02/2021 | CA Osasuna | - | Sevilla FC | 0:2 | ||||
| 38. Round | 23/05/2021 | Sevilla FC | - | CD Alavés | 1:0 | |
Spain
